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Genomic DNA was isolated from blood after obtaining
2019-06-10
Genomic DNA was isolated from blood after obtaining written informed consent. Genetic screening for LQT-1 (KCNQ1), -2 (KCNH2), -3 (SCN5A), -5 (KCNE1), -6 (KCNE2), -7 (KCNJ2), -9 (CAV3), -10 (SCN4B), and -12 (SNTA1) was performed by PCR and direct DNA sequencing. No order phenylephrine hydrochloride
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7-Nitroindazole Introduction Lung cancer is the most common
2019-06-10
Introduction Lung cancer is the most common and deadly malignancy in Taiwan, the cause of an estimated 33,919 new cases between 2002 and 2008. Although the 5-year survival rate is only 15.9%, the overall survival rate is as high as 60.7% in patients whose tumors are confined to the primary site at
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br Conflict of interest br Authors contributions br
2019-06-10
Conflict of interest Authors’ contributions Acknowledgements Introduction Aromatase-Inhibitors (AIs) are commonly used in the treatment of post-menopausal women with a history of hormone receptor-positive breast carcinoma, and have been shown to decrease bone mineral density (BMD) and in
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El texto de Paz nos permite contemplar el
2019-06-10
El texto de Paz nos permite contemplar el estado como una experiencia poética y una experiencia vital. Esto se debe en gran parte al énfasis que se pone en el cuerpo dnmt lo largo de , y más propiamente en el cuerpo que avanza en el sendero de Galta. La caminata física y la creación poética se prese
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br The past decade has seen increasing
2019-06-10
The past decade has seen increasing global policy attention to nutrition. Concrete steps have been taken to construct a global governance architecture for nutrition and also to mobilise resources for action. Efficacious, low-cost interventions exist, and there is greater consensus around technical
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Eosinophilia often occurs as a secondary process due to para
2019-06-10
Eosinophilia often occurs as a secondary process due to parasitic infections, allergy, mtor pathway disease, malignancy, or drug reactions. When secondary causes of eosinophilia are excluded, one must consider HES, which is defined as a peripheral eosinophil count of greater than 1.5×109/L on at le
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The points of agreement of
2019-06-10
The points of agreement of the models in the study by Brady and colleagues make sense—eg, it is intuitive that the post-MDA prevalence of malaria is strongly related to the proportion of individuals in the cyclooxygenase-2 inhibitors missed by an MDA campaign, as well as the pre-MDA endemic prevalen
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A total of microorganism species in the old
2019-06-10
A total of 46 microorganism species in the old NICU group and 35 in the new NICU group were isolated, respectively. Klebsiella pneumoniae was the most frequent pathogen in the old NICU group (Table 4), followed by E. coli, Methicillin-resistant Staphylococcus aureus (MRSA), Coagulase-negative Staphy
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MCL has a poor long
2019-06-10
MCL has a poor long-term response to current treatment strategies, for the most commonly used R-CHOP chemotherapy (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisolone), the remission rate is good (75–96%) but brief in duration. Despite the study of several other chemotherapy regimens
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br Sebastian Vollmer and colleagues April
2019-06-06
Sebastian Vollmer and colleagues (April, 2014) conclude that “the contribution of economic growth to the leukotriene receptor antagonists in early childhood undernutrition in developing countries is very small, if it exists at all”. Progress will therefore require a shift from “the so-called tric
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sigma 1 receptor br A KCNJ mutation corresponding to an S L
2019-06-06
A KCNJ8 mutation, corresponding to an S422L mutation in the protein, was first identified in a 14-year-old girl with early repolarization [59], who suffered frequent VF attacks. KCNJ8 encodes Kir6.1, which has 2 transmembrane regions, and the KATP channel is composed of a complex of Kir6.1 or Kir6
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There are limitations to the
2019-06-06
There are limitations to the current study. As with all surveys, there is an inherent bias in those that are contacted and in those that respond. Obtaining 90 responses on this topic is clearly important, however, the study would be strengthened by a greater number of responses. In addition, the maj
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In the case reported by Goldstein et al a
2019-06-06
In the case reported by Goldstein et al. [2], a Riata ST lead (St. Jude Medical, Sylmar, CA, USA) was used. The authors did not mention whether the lead was a dual-coil system or not. If the lead was a single-coil system, the possibility of an HV short circuit between the RV coil conductor and the d
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br Cardiac imaging br Head up tilt testing
2019-06-06
Cardiac imaging Head-up tilt testing Head-up tilt (HUT) testing is recommended to judge an episode of syncope to be likely caused by VF by excluding neurally mediated syncope (NMS). However, NMS may coexist with Brugada syndrome [42]. We conducted HUT testing in 46 patients with type-1 Brugada
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Numerous animal studies have demonstrated beyond doubt that
2019-06-06
Numerous animal studies have demonstrated beyond doubt that effective inhibition of osteoclastogenesis or osteoclast function significantly reduces metastatic tumour growth in bone [13–20]. Likewise, clinical trials in patients with non-metastatic or metastatic cancers established that treatment wit
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