• APJ receptor expression is altered in various

  2024-02-10

  

  APJ receptor expression is altered in various cardiovascular diseases, and both increases as well as decreases in APJ receptor expression have been reported. A decrease in mRNA and protein levels of APJ receptors was observed in patients with ischemic heart disease or idiopathic dilated cardiomyopat

• However one should keep in mind that these results

  2024-02-10

  

  However, one should keep in mind that these results may not reflect exactly in vivo antioxidant activity. Many other issues such as absorption, metabolism and physicochemical properties of different antioxidants must also be considered (Prior et al., 2007, Wu et al., 2004). Some research groups are

• In conclusion there are only

  2024-02-09

  

  In conclusion, there are only a few experimental reports evaluating the influence of Thymidine on allergy. With the exception of studies using macrolides, most point to their harmful effect on the severity of this disease. Future studies will be crucial to define the impact of antibiotic use on all

• Cell surface metalloproteases coordinate signaling during

  2024-02-09

  

  Cell surface metalloproteases coordinate signaling during development, tissue homeostasis, and disease. A disintegrin and metalloprotease 17 (ADAM17) is a well-characterized member among ADAM family, which mediates the cleavage of various cell surface proteins (Black, 2002, Black et al., 1997, Dello

• Since all the above vascular and glomerular effects contribu

  2024-02-09

  

  Since all the above vascular and glomerular effects contribute to blood pressure regulation, it is expected for 12/15-LOX pathway to play a role in pathogenesis of hypertension (Fig. 6). Indeed, there is evidence for alterations of the 12- and 15LOX enzymes and metabolites both in humans with essent

• br Conclusions br Introduction During numerous physiological

  2024-02-09

  

  Conclusions Introduction During numerous physiological processes, aldehydes are generated from a variety of endogenous and exogenous precursors including amino acids, carbohydrates, and lipids [1]. Most aldehydes are highly reactive and cytotoxic due to the strong electrophilic nature of the t

• The present study showed for

  2024-02-09

  

  The present study showed, for the first time, that hirsutine, hirsuteine, rhynchophylline, isorhynchophylline, corynoxeine, and isocorynoxeine in yokukansan can inhibit the 5-HT3 receptor current. These data indicate that part of the effect of yokukansan against the behavioral and psychological symp

• B lymphocytes are found in blood lymph

  2024-02-09

  

  B lymphocytes are found in blood, lymph nodes, spleen and tonsil and other mucosal tissues [110]. These cells originate in the bone marrow from a common progenitor shared with T, NK, and some DC subsets [111]. Progenitor 2-Guanidinoethylmercaptosuccinic Acid progress through the early stages of mat

• br Materials and methods br Results and

  2024-02-09

  

  Materials and methods Results and discussions Conclusion Fermented camel milk with NS4 exhibited remarkable ACE-inhibitory activity, which revealed its potential application for the preparation of fermented camel milk beverage or fermented camel milk derived peptides in different foods or i

• br Methods br Results From a study population of

  2024-02-09

  

  Methods Results From a study population of 7069 patients, a total of 149 falls were reported during the study growth hormone secretagogue for an incidence rate (IR) of 5.2 falls per 1000 patient-days (PD), 95% confidence interval (CI) 4.4/1000 PD–6.1/1000 PD. The incidence rate ratio (IRR) fo

• br Acknowledgments This work was supported

  2024-02-09

  

  Acknowledgments This work was supported by a grant of the Romanian National Authority for Scientific Research, CNCS – UEFISCDI, project no. PN-II-ID-PCE-2011-3-0571, awarded to F.A.M. D.V.N. was co-financed from the European Social Fund through Sectorial Operational Program Human Resources Develo

• In this scenario the receptor

  2024-02-09

  

  In this scenario, the receptor tyrosine kinase inhibitors (TKI), sunitinib, an anti-angiogenic agent, was tested in phase III trial, leading to a longer progressing free survival when compared to interferon (median: 11 vs. 5mo, respectively, hazard ratio (HR) = 0.42; 95% CI: 0.32–0.54; PFirefly Luci

• TUNEL assay Apoptotic DNA fragmentation in

  2024-02-07

  

  TUNEL assay. Apoptotic DNA fragmentation in Cyclo(RGDyK) was measured using a commercially available TUNEL assay kit (Thermo Fisher). Frozen cells were fixed with 10% paraformaldehyde/PBS. Apoptosis was determined by staining the 3′-OH ends of fragmented DNA with biotin-dNTP using DNA I klenow frag

• There is a delicate balance between

  2024-02-07

  

  There is a delicate balance between ROS generation and scavenging by the protective antioxidant defenses in the cell. Antioxidant systems present in the Schaftoside synthesis include enzymes like superoxide dismutase (SOD), catalases, glutathione peroxidases (GPxs) and peroxiredoxins (PRxs) (Fig. 3)

• Therefore in the present study

  2024-02-07

  

  Therefore, in the present study, we first examined the ATRAP MK-8931 in human leukocytes of healthy subjects. We next analyzed possible relevant clinical factors affecting ATRAP expression in leukocytes of patients with NCDs. Furthermore, we examined the possible effect of ATRAP downregulation on th

16226 records 202/1082 page Previous Next First page 上5页 201202203204205 下5页 Last page