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br Materials and methods br Results br Discussion
2019-12-19
Materials and methods Results Discussion Neointimal VSMC accumulation contributes considerably to vessel occlusion observed in both autologous vein graft degeneration [1], [2] and in-stent restenosis [26], [27]. In this study, the potential for retarding VSMC proliferation and hence amelior
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DBIBB The Fontan circulation When first described in the
2019-12-19
The Fontan circulation When first described in 1971, the Fontan operation ushered in a new paradigm in the care of children born with the varied forms of complex congenital DBIBB disease (CHD) characterized by a single effective pumping chamber.1., 2. This procedure, which creates a total cavopulm
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Developmental relationships between CD bright and CD dim
2019-12-19
Developmental relationships between CD56bright and CD56dim NK Sodium Orthovanadate remain unresolved; however, several studies indicate that the former is a precursor of the latter. An NK subset with intermediate features between CD56bright and CD56dim has been identified, corroborating this develo
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Each of these substrate receptors belongs
2019-12-19
Each of these substrate receptors belongs to a multigene family with tens, if not hundreds of members in plants, and with in part overlapping and in part differential substrate specificities [4]. The complexity of the system is nicely illustrated by the F-box protein and auxin receptor TRANSPORT INH
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br Discussion Although DNA has a limited chemical stability
2019-12-19
Discussion Although DNA has a limited chemical stability it has long been known that DNA in blood stains may remain relative stable for weeks, months, or even years at ambient temperature,1, 2, 3, 4, 5, 6 and samples (e.g., reference samples) that have been transferred to a matrix, e.g., FTA® pap
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In this study we reported
2019-12-18
In this study, we reported that over-expressed endogenous central ET-1 exerted anti-allodynic and anti-hyperalgesic effects on SNL-induced NP for the first time. Furthermore, we showed that ETA-R mRNA RSL3 together with the level of ET-1 was increased in the CNS up to 21days after SNL surgery in NTg
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In this regard http www apexbt com
2019-12-18
In this regard, some attempts have been made to reduce the presence of those radicals. In presence of fluorine source, it seems that the fluorine atoms can substitute the hydrogen atoms linked to silicon atoms, forming Si-F bonds with a higher bonding 7389 (536 kJ mo1−1) than the Si-H bonding energ
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br Materials and methods br Results br Discussion It
2019-12-18
Materials and methods Results Discussion It has been demonstrated that up-regulation of EPHB4 impaired trophoblast migration and invasion during placentation, which may contribute to the pathogenesis of preeclampsia [11], [24]. However, the upstream regulating mechanism of EPHB4 expression
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The Wnt signaling pathway has been
2019-12-18
The Wnt signaling pathway has been demonstrated to be responsible for a variety of biological processes. The three best-characterized Wnt signaling pathways are the canonical Wnt pathway, the noncanonical planar cell polarity pathway, and the noncanonical Wnt/calcium pathway. The canonical Wnt/β-cat
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br DUBs in regulation of critical steps
2019-12-18
DUBs in regulation of critical steps in tumor metastasis Tumor metastasis comprises a complicated series of biological processes in terms of the invasion-metastasis cascade that requires cancer neuronal nitric oxide synthase to (1) migrate and invade from the origin sites through the extracellul
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Funding sources This study was funded by European Community
2019-12-18
Funding sources This study was funded by European Community’s Seventh Framework Programme under grant agreement No. 305662 (Project: Community-based scheduled screening and treatment of malaria in pregnancy for improved maternal and infant health: a cluster-randomized trial ‘COSMIC’). Acknowledg
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br Conclusions This report describes the discovery of
2019-12-18
Conclusions This report describes the discovery of a new class of host-directed antiviral agents characterized by a 1-aryl-4,6-diamino-1,2-dihydrotriazine scaffold, responsible for a host (human) DHFR inhibition mechanism. Host-targeting antivirals represent an alternative and emerging strategy t
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br Hypothesis on DDR protective mode
2019-12-18
Hypothesis on DDR1 protective mode of action The documented protective role of DDR1 is quite impressive, demonstrated using different preclinical models (immunologic [46,54,58], obstructive [45], and hypertensive [50]) with different intervention paradigms: genetic ablation [45,50,58,72], silenci
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A range of therapies exists for the treatment of inflammatio
2019-12-18
A range of therapies exists for the treatment of inflammation-driven diseases, which can be summarized as non-steroidal anti-inflammatory drugs (NSAIDs), corticoids and steroidal-related drugs (Ward et al., 2008). Despite of these notable successes, there are still major unmet medical needs in the t
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ornidazole To characterize Ea and S DC
2019-12-18
To characterize Ea and γ·S, DC/AC electrical parameters will be determined from MIL standard measurements in a temperature range of −55 to +200°C. It is therefore necessary also to characterize the junction temperatures and hot points by infra-red or electrical method. The accelerated aging, represe
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