• In the present study we firstly confirmed

  2019-07-01

  

  In the present study, we firstly confirmed the resistance of osteosarcoma U2OS SGC707 structure to doxorubicin under hypoxia via inhibiting the drug-induced apoptosis. The hypoxia pre-treatment could significantly ameliorate the viability reduction in U2-os cells which were treated with doxorubicin

• A first step is reconsideration of the term family

  2019-07-01

  

  A first step is reconsideration of the term family planning. This debate is not simply a question of semantics—language is a powerful ideological and political statement. Discourse creates a representation of the world; it perpetuates a cultural and social reality. In this sense, language is action,

• Buturovic and Ignatovic rightly point out that present

  2019-07-01

  

  Buturovic and Ignatovic rightly point out that present-day formula is different from the type of milk received by Brazilian infants born in the early 1980s, particularly because long-chain polyunsaturated fatty acids have been added to modern products. Nevertheless, modern biology is constantly unco

• br A manera de conclusi n

  2019-07-01

  

  A manera de conclusión El periódico La Lucha mantuvo una postura contra la intervención estadounidense en el proceso independentista cubano de 1895. Misma que refrendó en la coyuntura de la imposición de la Enmienda Platt. En esa ocasión utilizó un lenguaje grandilocuente que vislumbraba un futur

• br Algorithm of treatment approach in

  2019-06-29

  

  Algorithm of treatment approach in Brugada syndrome patients with electrical storm Fig. 4 shows the flow diagram of how we treat BrS patients with ES. Patients are admitted to the ICU and should be well sedated, and some may require general anesthesia with endotracheal intubation. The patients ar

• Introduction Personalized medicine is the major

  2019-06-29

  

  Introduction Personalized medicine is the major goal of translational research in the post-genomic era. Numerous biomarkers have been identified by genomic or proteomic approach that can reclassify the disease VSV-G Peptide and predict clinical outcome. However, to define a specific disease phenot

• br Conflict of interest br Introduction Garrigue et

  2019-06-29

  

  Conflict of interest Introduction Garrigue et al. reported that atrial overdrive pacing reduces the number of sleep Results episodes in pacemaker patients without heart failure [1]. However, this finding has not been replicated in subsequent investigations [2–5], although some meta-analysis s

• Atrial fibrosis is one of the fundamental mechanisms

  2019-06-29

  

  Atrial fibrosis is one of the fundamental mechanisms for the pathogenesis of atrial fibrillation (AF), but the underlying electrophysiological changes involved are not completely understood. Aging, neurohumoral activation, and chronic atrial stretch due to structural heart disease activate various s

• br Discussion The mechanism of verapamil sensitive ILVT

  2019-06-29

  

  Discussion The mechanism of verapamil-sensitive ILVT has been suggested as re-entry with an excitable gap and a slow conduction, because the VT can be induced, entrained, and terminated by programmed ventricular or atrial stimulation [1–6]. In addition, previous studies have suggested that the re

• product For HL most previous studies have

  2019-06-29

  

  For HL, most previous studies have shown a correlation between decreasing survival rates for patients with HL with decreasing SES, although several studies found no or a varied association between survival outcomes in patients with HL with decreasing SES. The differences in these findings may be att

• Preclinical studies have shown that

  2019-06-29

  

  Preclinical studies have shown that adipocytes and MSCs play an important role in migration and dissemination of cancer Vicriviroc Malate molecular [55,56]. Concerning osteosarcoma, one publication has reported that human MSCs injected through the caudal vein of mice bearing Saos-2- induced an incr

• Causative genes for ARVC and their respective

  2019-06-29

  

  Causative genes for ARVC and their respective characteristics are summarized in Table 1. Desmosome genes for ARVC Other causative genes for ARVC Although more than half of ARVC patients carry mutations in desmosome genes, other genes have also been reported as causative genes for ARVC (Table

• AC regimens have also demonstrated better preventive effects

  2019-06-29

  

  AC regimens have also demonstrated better preventive effects in terms of stroke than AP regimens [18–20], whereas major or minor bleeding events in Japanese patients with cardiovascular diseases were reported to be more frequent in patients taking AC than in those taking AP regimens [21]. To underst

• Hasta el tercer acto cuando Licurgo

  2019-06-29

  

  Hasta el tercer acto, cuando Licurgo se casa y vuelve Spironolactone la racionalidad, presenta al Rey una serie de leyes, quien, sin conocerlas, le pregunta si desea hacerlas públicas, pero, desde otra óptica, Licurgo responde: Son, pues, el Rey y el Reino quienes deben acordar las leyes, para evit

• Ideally assessment of obstetric interventions

  2019-06-29

  

  Ideally, assessment of obstetric interventions and outcomes should be based on high-quality, recent data from the entire population or a representative sample. A key feature of the Robson classification is that it uses information that is available at the onset of labour or delivery, is routinely co

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