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br Interpretation of identified genetic
2019-04-17
Interpretation of identified genetic variants and genetic counseling Although the current expert consensus statement recommends that comprehensive or BrS1 (SCN5A) targeted BrS genetic testing can be useful for genetic testing [63], not all the published SCN5A mutations in BrS have been subjected
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Most forms of AVNRT are created by reentry between two
2019-04-17
Most forms of AVNRT are created by reentry between two (or more) atrial connections to the AV node. The fast AV nodal pathway (shortest conduction time) is formed by transitional cells crossing the tendon of Todaro superiorly. Two slow AV nodal pathways are formed by the rightward and leftward infer
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order Sulindac sulfide En las relaciones pol ticas tradicion
2019-04-17
En las relaciones políticas tradicionales mapuche, el longko o autoridad tuvo la función de repartir las tierras, prerrogativa que perdió con los desplazamientos y las reducciones, situación que en unión al hecho de que los distintos gobiernos regidos por la intención del trato igualitario para los
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Benjam n Arditi por su parte ha
2019-04-17
Benjamín Arditi, por su parte, ha desarrollado parte de su obra en diálogo con y contra Laclau. En lo que nos ocupa, en una extensa reseña de La razón populista, Arditi repara en la triple sinonimia de populismo, hegemonía y política y, además, lanza un conjunto de observaciones agudas. Al igual que
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br The paper in by Victoria Fan and colleagues is
2019-04-17
The paper in by Victoria Fan and colleagues is important because it describes what several people close to the Global Fund to fight AIDS, Tuberculosis and Malaria already know: there is a problem with its disbursement mechanisms. Fan and colleagues correctly state that the Global Fund should “red
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Ante la necesidad de unas reglas
2019-04-17
Ante la necesidad de unas reglas o códigos ret pathway partir de los cuales evaluar la producción de los decadentistas, el autor del artículo se lamenta de su inexistencia: “¿Dónde está el código de los decadentistas? No le tienen porque en vez de reglas lo que ellos practican es la violación capric
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En este contexto a juicio de Svampa
2019-04-17
En este contexto, Cy3 hydrazide juicio de Svampa, cohabitan en el campo contestatario latinoamericano cuatro matrices político-ideológicas que dan cuenta de diferentes perspectivas en relación con la manera de pensar la política y el poder, así como los procesos de cambio social. Estas matrices son
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br The estimated number of women who die each
2019-04-16
The estimated number of women who die each year from causes related to pregnancy or childbirth has dropped substantially—from 543 000 deaths in 1990 to about 287 000 in 2010. Nevertheless, maternal mortality ratios remain among the least equitable of all health indicators, ranging from less than f
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Two other groups subsequently published further data on iPSC
2019-04-16
Two other groups subsequently published further data on iPSCs models of ARVC that have improved our understanding of this disease. Kim et al. developed iPSC models using episomal methods from 2 ARVC patients, as well as with PKP2 mutations . Detailed electrophysiological characterization of mutant a
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Preference for injectable therapy over oral therapy contrary
2019-04-16
Preference for injectable therapy over oral therapy [17], contrary to our findings from a previous study [18], could reflect the fact that most patients have not received an oral bone-targeted agent for metastatic disease. However, the practical advantages of an injectable therapy and the lack of ne
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AC regimens have also demonstrated better
2019-04-16
AC regimens have also demonstrated better preventive effects in terms of stroke than AP regimens [18–20], whereas major or minor bleeding events in Japanese patients with cardiovascular diseases were reported to be more frequent in patients taking AC than in those taking AP regimens [21]. To underst
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Introduction Multiple myeloma MM is the most frequent cancer
2019-04-15
Introduction Multiple myeloma (MM) is the most frequent cancer to involve the skeleton with 80–90% of patients developing bone lesions during their disease course [1]. Myeloma bone lesions are purely osteolytic and are associated with severe and debilitating bone pain, pathologic fractures, hyperca
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The miR signature of exosomes isolated from bulk
2019-04-15
The miR signature of exosomes isolated from bulk prostate cancer atp citrate lyase (Fig. 1A, blue cells) and from their cancer stem cell compartment (Fig. 1A, green cells), display high levels of miR-21, miR-30 and miR-218 [23] (Fig. 1A, blue arrow). miR-21 and miR-30 have been identified as key r
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Common and rare SCN A variants may contribute
2019-04-15
Common and rare SCN10A variants may contribute to AF susceptibility [59,60]. SCN10A mutations (R14L and R1268Q) cause a loss of function of Nav1.5 current, which is expected to reduce excitability and lead to the development of the arrhythmogenic substrate responsible for BrS and AF. A common varian
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The Millennium Development Goals MDGs have
2019-04-15
The Millennium Development Goals (MDGs) have become key targets for the international lxr agonists over the past 15 years. The MDGs have raised awareness, focused global efforts on agreed priorities, and empowered so-called development champions at country level. This progress was less straightforw
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